Gadolinium in PDB 1isr: Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion

The structure of Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion, PDB code: 1isr was solved by D.Tsuchiya, N.Kunishima, N.Kamiya, H.Jingami, K.Morikawa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 4.00
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	145.348, 145.348, 76.754, 90.00, 90.00, 120.00
R / Rfree (%)	23.7 / 25.9

The binding sites of Gadolinium atom in the Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion (pdb code 1isr). This binding sites where shown within 5.0 Angstroms radius around Gadolinium atom.
In total 2 binding sites of Gadolinium where determined in the Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion, PDB code: 1isr:
Jump to Gadolinium binding site number: 1; 2;

Gadolinium binding site 1 out of 2 in the Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion


Mono view


Stereo pair view

A full contact list of Gadolinium with other atoms in the Gd binding site number 1 of Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion within 5.0Å range: probe atom residue distance (Å) B Occ A:Gd2001 b:19.9 occ:1.00 OD2 A:ASP493 2.5 64.8 1.0 OD1 A:ASP493 2.6 64.8 1.0 CG A:ASP493 2.9 64.8 1.0 CB A:ASP493 4.4 64.8 1.0 OD1 A:ASP324 4.6 48.0 1.0 OD2 A:ASP324 4.6 48.0 1.0 N A:TYR494 4.7 64.8 1.0 NH2 A:ARG491 4.9 0.8 1.0 O A:TYR494 4.9 64.8 1.0

Gadolinium binding site 2 out of 2 in the Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion


Mono view


Stereo pair view

A full contact list of Gadolinium with other atoms in the Gd binding site number 2 of Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion within 5.0Å range: probe atom residue distance (Å) B Occ A:Gd2002 b:14.2 occ:0.50 OE2 A:GLU238 3.4 78.7 1.0 CD A:GLU238 3.8 78.7 1.0 OD1 A:ASP242 3.9 78.7 1.0 CG A:GLU238 4.0 78.7 1.0 OD2 A:ASP242 4.1 78.7 1.0 CG A:ASP242 4.4 78.7 1.0 OE1 A:GLU238 4.5 78.7 1.0

D.Tsuchiya, N.Kunishima, N.Kamiya, H.Jingami, K.Morikawa. Structural Views of the Ligand-Binding Cores of A Metabotropic Glutamate Receptor Complexed with An Antagonist and Both Glutamate and GD3+. Proc.Natl.Acad.Sci.Usa V. 99 2660 2002.
ISSN: ISSN 0027-8424
PubMed: 11867751
DOI: 10.1073/PNAS.052708599